| Jornada 1 - Fase Grupo | 2021-09-16 18:45:29jueves, 16/09/2021 | Real Betis  | 4 - 3 |  Celtic de Glasgow | Europa League | 21-22 | N/D | Prensa |
Fran Jovic |
Bastian Dankert |
30.893 |
GolTV |
| Jornada 2 - Fase Grupo | 2021-09-30 21:00:44jueves, 30/09/2021 | Ferencváros TC  | 1 - 3 | Real Betis | Europa League | 21-22 | N/D | Prensa |
Roi Reinshreiber |
Ziv Adler |
14.200 |
GolTV |
| Jornada 3 - Fase Grupo | 2021-10-21 18:45:54jueves, 21/10/2021 | Real Betis | 1 - 1 |  Bayer Leverkusen | Europa League | 21-22 | N/D | Prensa |
Bartosz Frankowski |
Tomasz Kwiatkowski |
39.230 |
Movistar |
| Jornada 4 - Fase Grupo | 2021-11-04 21:00:34jueves, 04/11/2021 | Bayer Leverkusen | 4 - 0 | Real Betis | Europa League | 21-22 | N/D | Prensa |
Anthony Taylor |
Stuart Attwell |
15.208 |
Movistar |
| Jornada 5 - Fase Grupo | 2021-11-25 18:45:39jueves, 25/11/2021 | Real Betis | 2 - 0 | Ferencváros TC | Europa League | 21-22 | N/D | Prensa |
Ruddy Buquet |
Delajod Willy |
30.137 |
GolTV |
| Jornada 6 - Fase Grupo | 2021-12-09 21:00:16jueves, 09/12/2021 | Celtic de Glasgow | 3 - 2 | Real Betis | Europa League | 21-22 | N/D | Prensa |
Daniel Stefanski |
Pawel Raczkowski |
54.548 |
GolTV |
| 1/16 Europa League | 2022-02-17 18:45:31jueves, 17/02/2022 | FC Zenit  | 2 - 3 | Real Betis | Europa League | 21-22 | N/D | Prensa |
Benoit Bastien |
Amaury Delerue |
28.936 |
Movistar |
| 1/16 Europa League | 2022-02-24 21:00:51jueves, 24/02/2022 | Real Betis | 0 - 0 | FC Zenit | Europa League | 21-22 | N/D | Prensa |
Halil Umut Meler |
Paolo Valeri |
44.236 |
GolTV |
| 1/8 Europa League | 2022-03-09 18:45:18miércoles, 09/03/2022 | Real Betis | 1 - 2 |  Eintracht Frankfurt | Europa League | 21-22 | N/D | Prensa |
Marco Guida |
Massimiliano Irrati |
36.574 |
Movistar |
| 1/8 Europa League | 2022-03-17 21:00:15jueves, 17/03/2022 | Eintracht Frankfurt | 1 - 1 | Real Betis | Europa League | 21-22 | N/D | Prensa |
Michael Oliver |
Chris Kavanagh |
25.000 |
Movistar |
